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It could be Pear Leaf Blister Mite. If so, there's not much you can do but it is said to not significantly affect the health or fruiting ability of the tree.
The advice above is to remove affected leaves and shoots but doing that may cause more harm than good if most of the tree is affected:
Many thanks for the suggestion. Having now looked up images and information online, I think you are spot on and it is exactly a very bad Pear Leaf Blister Mite infestation.
As the whole tree is now affected, removing the leaves is just not an option, but I am finding a number of different suggestions online, some organic, some not, which I will try out.
Thanks again for your help.
I hope you find something which works, Mario. If you have any success, it would be helpful to other members if you can post back your results. There was another thread recently suspecting this disease and I wonder if the mild Winter we had means many more of the mites have survived than is normally the case.
Lots of fungal spores will be about this year - she said cheerfully - so my advice is feed your plants to boost their health. *
Washing new grape growth with a 30% milk, or 10% yogurt, to water solution can protect from some mildews. Something in the milk cultures seems to deter the mildew from kicking off. Don't know if it works on other fruit leaves though.
*seaweed feed, chicken pellets, blood fish and bone etc will also help sandy soils that have had nutrients leeched out by rain.
I hope your patient recovers Mario, Good Luck!