I've only a small garden and have lost many plants, previousy hardy here for the last 10 years. My Ceanothus Concha, the pale green Pittosporum and the Clematis napulensis, both grown from from seed. Even the foliage of my rose Mermaid, has had all its shoots frosted off, but will, I hope, survive.
Though I grieve their passing, in such a small space it does offer new planting opportunities and a chance to move things round. Gardens (and life) would be boring without change.